EPAD - European Prevention of Alzheimer's Dementia

European Prevention of Alzheimer's Dementia

- Newsletter April 2018 -

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Welcome

Dear Friends and Colleagues,

EPAD is slowly coming of age. Recruitment in the Longitudinal Cohort Study (LCS) has picked up significantly in the first quarter of 2018 with currently 640 research participants enrolled in 14 Trial Delivery Centers (TDCs), thereby more than doubling the monthly recruitment rate and the number of active TDCs compared to December 2017. Over the next months, we will continue to see these numbers rise as IQVIA, Sponsor and supporting EPAD Recruitment Task Force open more sites while at the same time continue to work with already recruiting TDCs to share best practices, boost, and even more importantly, maintain these recruitment levels into the LCS.

I am also happy to announce that after 2 years of hard work, the EPAD Proof-of-Concept (PoC) trial platform is ready to receive interventions for testing in a secondary prevention population. With another 4 companies announcing arresting development of promising Alzheimer drugs since the beginning of 2018, the need for EPAD and the EPAD PoC platform is greater than ever. An observation that is finding confirmation in the increasing number of pharmaceutical companies that are currently in discussion with EPAD’s Clinical Candidate Selection Committee. In further support of developing the EPAD interventional pipeline, EPAD will host a satellite symposium specifically for potential intervention owners at the 2018 AAIC in July and be present in the exhibition center with a dedicated EPAD booth. So be sure to come visit us at our booth when you are attending AAIC in Chicago.

Less than a month from now we will all meet in Amsterdam for the 2018 EPAD General Assembly which will be hosted by Prof. Scheltens and his team at VUmc. We have put together an interesting agenda and hope that you are all able to join us for a few exciting days in Amsterdam. In case you still need to register, just click Register for EPAD GA.

EPAD has gotten off to a great start in 2018 and I am confident that we can continue to build on this momentum and make this the best EPAD year ever. I would like to close by thanking all of you, no matter what your role in EPAD is, EPAD is where it is today because of you. THANK YOU, and hope to see you in Amsterdam.

This electronic newsletter will be published quarterly and be accessible via the EPAD website (https://ep-ad.org) to inform the Alzheimer’s community on EPAD’s main achievements and upcoming events as well as allowing you to meet the scientists who make it all happen.  

We hope you enjoy this issue of the EPAD newsletter! Happy reading!

Serge Van der Geyten

EPAD Coordinator

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EPAD has new TDCs on board

Q1 2018 Highlights

EPAD has new TDCs on board

The first quarter of 2018 started with great intensity! We were busy working towards opening new sites and improving recruitment. Positive results of our work have begun to come out in a short time with specific progress achieved. First of all, we are delighted to have reached a big milestone in February 2018 when our EPAD Longitudinal Cohort Study (LCS) …

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EPAD invited to speak at AE Lunch Debate focused on dementia prevention

The Story behind the picture

EPAD invited to speak at AE Lunch Debate focused on dementia prevention

On 27 February, our partner Alzheimer Europe (AE) held a successful lunch debate entitled “Will we be able to prevent Alzheimer’s dementia” at the European Parliament in Brussels (Belgium). The lunch debate focused on the prevention of Alzheimer’s disease (AD) and dementia through three key presentations. The panel included a presentation by the European Prevention of Alzheimer’s dementia (EPAD) initiative. …

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Meet the EPAD team

Interview with Harry Peaker

Interview with Harry Peaker

What is your current role in EPAD? As a Data Scientist at Aridhia, I support the development and maintenance of the Analytical Database for the EPAD Longitudinal Cohort Study. IQVIA securely transfer the collated project data from their EDC platform (Medidata Rave) to our digital research platform (AnalytiXagility) on a regular basis. We transform the data into the Health Analytics …

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Interview with Sarah Gregory

Interview with Sarah Gregory

What is your current role in EPAD? I coordinate EPAD at the Edinburgh Trial Delivery Centre, working with a great team of research assistants, study doctors and research nurses to deliver the protocol. I oversee the daily running of the study in our TDC, making sure we have sufficient recruitment avenues to bring in new participants, that we have enough …

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EPAD design

EPAD presents @

• The EPAD General Assembly Meeting will take place in Amsterdam (The Netherlands) from 23 to 25 May 2018.

• A number of EPADistas will be present at this year's Alzheimer's Association International Conference AAIC 2018 in Chicago (US) from 22 to 26 July 2018.

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Quarterly Quote

“However difficult life may seem, there is always something you can do and succeed at”

 Stephen Hawking -

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