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Alzheimer's Q&A

What is dementia?


Dementia is an umbrella term used to describe a set of symptoms that can include memory loss, confusion, and difficulties with language. There are many different types of dementia. These occur when the brain is affected by certain diseases or conditions.



What is Alzheimer's dementia?


Alzheimer’s disease can cause a specific type of dementia that usually develops slowly and gets worse over time. During the disease, proteins build up in the brain to form structures called ‘plaques’ and ‘tangles’. This can lead to the loss of connections between nerve cells, and eventually to the loss of brain tissue. There are currently no treatments or cures for Alzheimer’s dementia.



How many people are affected by Alzheimer’s dementia?


There are an estimated 46.8 million people worldwide living with dementia in 2015 and this figure is set to rise to 131.5 million by 2050. (World Alzheimer Report 2016). Alzheimer’s disease is the leading cause of dementia globally. It affects around seven million people in Europe.



Why are you focusing on prevention rather than treatment?


Attempts to develop new therapies for treating Alzheimer’s disease have so-far been unsuccessful. It is a progressive disorder and it is well known that the signs of the disease – plaques and tangles – can be found in the brain decades before the first symptoms appear. Researchers believe that early intervention may be a more effective way to tackle the condition.


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If you're attending #BNA2021, check out the pre-registration poster from @GregorySarah introducing the SPeAk study. Participants of this new study must have previously enrolled in the @IMI_EPAD LCS or CHARIOT Pro study at @CenDemPrevent. #biomarker #Alzheimer’s disease #dementia twitter.com/CenDemPrevent/…

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10:18 am · 2021-04-14
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Check out the last @IMI_EPAD publication on the application of the #ATN classification scheme in the first 1500 participants consented in the EPAD Longitudinal Cohort Study. ep-ad.org/2021/04/06/new… @silvia_ingala @IMI_JU @EFPIA @EU_H2020 pic.twitter.com/3HhgMcBDN0

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8:15 am · 2021-04-13
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The @IMI_EPAD Bioresource consists of over 100,000 samples consisting of blood, CSF, saliva and urine that have been collected annually from research participants throughout their participation in the Longitudinal Cohort Study. #OpenAccess ep-ad.org/2021/03/10/epa… twitter.com/IMI_EPAD/statu… pic.twitter.com/dRjuI1opFi

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7:16 am · 2021-04-12
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The ATN classification has been added for public use to the analytical database of the @IMI_EPAD Longitudinal Cohort Study, hosted by @aridhia . ⬇️ ep-ad.org/2021/04/06/new… twitter.com/IMI_EPAD/statu…

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5:56 am · 2021-04-07
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In this article, the #ATN classification was operationalized in the first 1500 participants consented in the @IMI_EPAD cohort, a deeply phenotyped cohort of individuals who do not have #dementia. ep-ad.org/2021/04/06/new…

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7:08 am · 2021-04-06
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This work has received support from the EU/EFPIA Innovative Medicines Initiative Joint Undertaking EPAD grant agreement nº 115736

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