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New ERC starting grant to identify age-related human blood factors as a therapeutic target for Alzheimer’s disease

2020-09-10News

The European Research Council has awarded an Early Career Research (ERC) starting grant to the neurologist Marc Suárez-Calvet, MD, PhD, who will use data from the EPAD Longitudinal Cohort Study for his new project entitled “Identification of age-related Human Blood factors as a therapeutic target for Alzheimer’s disease” (acronym: HeBe).

The overall aim of the project, named after the Ancient Greek goddess of eternal youth, is to discover blood factors with a rejuvenating or ageing effect on the human brain that could become therapeutic targets for Alzheimer’s disease and other age-related brain diseases.

Marc Suárez-Calvet will define extreme biological age phenotypes in participants of the Alfa + study, conducted at the Barcelonaβeta Brain Research Center (BBRC), based on the difference between biological and chronological age. Afterwards, he will use advanced proteomics and metabolomics to measure these factors in BBRC’s cohort, but also in research participants from the EPAD Longitudinal Cohort Study.

The main hypothesis of the awarded project is that higher levels of rejuvenating blood factors decrease the rate of neurodegeneration, while higher levels of ageing blood factors increase the rate of neurodegeneration.

The study will be performed at BBRC, where the researcher was working over the last two years with a Marie Skłodowska-Curie Grant, in collaboration with the University of Göteborg.

For more information, please contact Marc Suárez-Calvet via email (msuarez@barcelonabeta.org) or Twitter (@M_SuarezCalvet).

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  1. Pingback: The ERC has awarded an ERC grant to identify age-related human blood factors as a therapeutic target for Alzheimer’s disease – Neuronet

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Latest News
  • Closing EPAD article published in the Alzheimer Europe magazine
    2021-02-24
  • Alzheimer Europe launches a report on data sharing in dementia research
    2021-02-23
  • Local actions to keep the EPAD Longitudinal Cohort data collection going
    2021-02-17
  • Neuronet releases its Knowledge Base dashboard
    2021-02-01
  • The final EPAD dataset is now available to the entire research community
    2020-11-30
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@AD_PREVENT @alzassociation @alzheimerssoc Congratulations to all the team 👏

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7:03 am · 2021-03-01
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.@AlzheimerEurope has published a new edition of its “Dementia in Europe” magazine. It includes a closing article on @IMI_EPAD. Our co-leads @craig_ritchie68 and Serge Van der Geyten, reflect on the achievements of the project. Download the PDF here: bit.ly/DementiaInEuro… twitter.com/AlzheimerEurop…

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12:40 pm · 2021-02-24
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Last week, we held the first local @IMI_EPAD community meeting among the Scottish research sites, collaborators, academics & scientists who have been involved in our Longitudinal Cohort Study and now continue to contribute to the study locally More info⤵️ ep-ad.org/2021/02/17/loc… pic.twitter.com/MTKmanCURk

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6:51 am · 2021-02-24
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Check out the new @AlzheimerEurope report on #DataSharing in #dementia #research, which reviews recent changes in EU research policy and sets out recommendations to improve data sharing. It includes case studies from ADNI, @IMI_EPAD and @IMI_EMIF. ⬇️ Bit.ly/DataSharing_AE twitter.com/AlzheimerEurop…

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2:39 pm · 2021-02-23
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Scottish @IMI_EPAD members have been invited to join the first #EPADcommunity meeting. Today, we're discussing about publications, #data access, communications, participant panel, #network & #collaborations. Nice to see some #epadistas sharing their insights 👨‍⚕️👩‍🔬👩‍💻 pic.twitter.com/O1hLAVxk0Q

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2:23 pm · 2021-02-17
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