{"id":10469,"date":"2025-02-04T09:06:35","date_gmt":"2025-02-04T08:06:35","guid":{"rendered":"https:\/\/ep-ad.org\/?p=10469"},"modified":"2025-02-04T09:06:35","modified_gmt":"2025-02-04T08:06:35","slug":"amyloid-beta-accumulation-confirmed-to-cause-early-brain-damage-in-alzheimers","status":"publish","type":"post","link":"https:\/\/ep-ad.org\/index.php\/2025\/02\/04\/amyloid-beta-accumulation-confirmed-to-cause-early-brain-damage-in-alzheimers\/","title":{"rendered":"Amyloid beta accumulation confirmed to cause early brain damage in Alzheimer&#8217;s"},"content":{"rendered":"\n<p>A study by the Barcelona\u03b2eta Brain Research Center (BBRC), a research center of the Pasqual Maragall Foundation, has identified that <strong>the accumulation of beta amyloid can, on its own, cause brain damage in the early stages of Alzheimer&#8217;s<\/strong>, even without elevated levels of the tau protein. This work, published in the journal <em>Alzheimer&#8217;s &amp; Dementia: The Journal of the Alzheimer&#8217;s Association<\/em>, assessed brain atrophy and cognitive decline in two independent cohorts of asymptomatic individuals: ALFA and EPAD.<\/p>\n\n\n\n<p>\u201c<em>In recent years, the first drugs have been approved to reduce the accumulation of beta amyloid in the brain of people in the early stages of Alzheimer&#8217;s. This advance suggests that intervening at early stages, before symptoms appear, could slow the progression of the disease. Beta amyloid appears to directly affect the hippocampus, a key region for memory, so acting early could significantly reduce the risks associated with Alzheimer&#8217;s<\/em>,\u201d says <strong>Dr. Raffaele Cacciaglia, BBRC researcher and leader of the study.<\/strong><\/p>\n\n\n\n<p>You can read the paper here: <a href=\"https:\/\/doi.org\/10.1002\/alz.14415\">https:\/\/doi.org\/10.1002\/alz.14415<\/a><\/p>\n\n\n\n<p>You can read the BBRC press release here: <a href=\"https:\/\/www.barcelonabeta.org\/en\/news\/press\">https:\/\/www.barcelonabeta.org\/en\/news\/press<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study by the Barcelona\u03b2eta Brain Research Center (BBRC), a research center of the Pasqual Maragall Foundation, has identified that the accumulation of beta amyloid can, on its own, cause brain damage in the early stages of Alzheimer&#8217;s, even without elevated levels of the tau protein. This work, published in the journal Alzheimer&#8217;s &amp; Dementia: [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":10470,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-10469","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/posts\/10469","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/comments?post=10469"}],"version-history":[{"count":1,"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/posts\/10469\/revisions"}],"predecessor-version":[{"id":10471,"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/posts\/10469\/revisions\/10471"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/media\/10470"}],"wp:attachment":[{"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/media?parent=10469"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/categories?post=10469"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ep-ad.org\/index.php\/wp-json\/wp\/v2\/tags?post=10469"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}