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European Prevention of Alzheimer's Dementia Consortium
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Samples

The EPAD Bioresource consists of over 100,000 samples consisting of blood, CSF, saliva and urine that have been collected annually from research participants throughout their participation in the Longitudinal Cohort Study. The samples are stored in -20°C, -80°C or -150°C freezers as appropriate at the EPAD Bioresource facility located at the Roslin Institute, University of Edinburgh. The Bioresource team utilizes a bespoke lab database and information management system that provides traceability and sample validation at every stage along the sample pathway, from collection, processing, storage and release for research.

Sample Type Stored As
Blood
  • Buffy Coat
  • Plasma SCT
  • Plasma EDTA
  • PAXgene
  • Peripheral Blood Monocytes
  • Serum
  • DNA
CSF
  • CSF processed (centrifugation)
  • CSF unprocessed
Saliva
  • Cortisol Salivettes
  • Drooling Sample
Urine
  • Processed/Centrifuged

 

About the EPAD LCS Sample Access Committee

The EPAD Longitudinal Cohort Study (LCS) Sample Access committee consists of international experts in the field of dementia and its primary purpose is to ensure that researchers make best use of the EPAD samples.  The committee conducts a scientific review of applications and assesses requests on four broad areas: (i) Significance, e.g. will the project progress research in Alzheimer’s disease prevention; (ii) Investigator expertise, experience and training; (iii) Innovation, e.g.  is the research novel and innovative; and (iv) Approach, e.g. are the strategy, methodology, sample size, data management approach and statistical analyses well-reasoned.

How do I apply?

EPAD offers a way of accessing the samples collected during the EPAD LCS. Applications are made through a system called Wizehive, you will need to make an online request here.

 

“We aim to ensure that this precious collection of samples is put to the very best use towards the prevention of Alzheimer’s dementia.”

Jean Manson
PI of the EPAD Bioresource and Chair of the Sample Access Committee
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Latest News
  • Closing EPAD article published in the Alzheimer Europe magazine
    2021-02-24
  • Alzheimer Europe launches a report on data sharing in dementia research
    2021-02-23
  • Local actions to keep the EPAD Longitudinal Cohort data collection going
    2021-02-17
  • Neuronet releases its Knowledge Base dashboard
    2021-02-01
  • The final EPAD dataset is now available to the entire research community
    2020-11-30
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The latest @AlzheimerEurope #newsletter includes an article on the first local @IMI_EPAD community meeting held last month among the Scottish research sites and collaborators who have been involved in the EPAD Longitudinal Cohort Study. Read more here: bit.ly/Feb2021AEnews twitter.com/AlzheimerEurop…

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3:26 pm · 2021-03-03
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@AD_PREVENT @alzassociation @alzheimerssoc Congratulations to all the team 👏

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7:03 am · 2021-03-01
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.@AlzheimerEurope has published a new edition of its “Dementia in Europe” magazine. It includes a closing article on @IMI_EPAD. Our co-leads @craig_ritchie68 and Serge Van der Geyten, reflect on the achievements of the project. Download the PDF here: bit.ly/DementiaInEuro… twitter.com/AlzheimerEurop…

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12:40 pm · 2021-02-24
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Last week, we held the first local @IMI_EPAD community meeting among the Scottish research sites, collaborators, academics & scientists who have been involved in our Longitudinal Cohort Study and now continue to contribute to the study locally More info⤵️ ep-ad.org/2021/02/17/loc… pic.twitter.com/MTKmanCURk

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6:51 am · 2021-02-24
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Check out the new @AlzheimerEurope report on #DataSharing in #dementia #research, which reviews recent changes in EU research policy and sets out recommendations to improve data sharing. It includes case studies from ADNI, @IMI_EPAD and @IMI_EMIF. ⬇️ Bit.ly/DataSharing_AE twitter.com/AlzheimerEurop…

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2:39 pm · 2021-02-23
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