Find the latest in EPAD news and research

Development of interventions for the secondaryprevention of Alzheimer’s dementia: the EuropeanPrevention of Alzheimer’s Dementia (EPAD) project

Ethical challenges in preclinical Alzheimer’s diseaseobservational studies and trials: Results of theBarcelona summit

“Polygenic pathways shape white matter vulnerability to Alzheimer’s disease-related pathophysiological changes” Authors: Mario Tranfa, Leonard Pieperhoff, Giuseppe Pontillo, Emma S. Luckett,…

“Cortical thickness subtypes in cognitively unimpaired individuals: Differential network and transcriptomic vulnerability to cortical thinning” Authors: Luigi Lorenzini, Mario Tranfa, Leonard…

“Early detection of Alzheimer’s disease using small RNAs. Results from the EPAD cohort” Authors: Tobias Sikosek , Marco Heuvelman, Jagoda Mika,…

“Blood pressure and Alzheimer’s disease biomarkers in cognitively unimpaired adults: a multicenter study” Authors: Mariona Osset-Malla, Aitana Martínez-Velasco, Gonzalo Sánchez-Benavides ,…

“Brain MRI signatures across sex and CSF Alzheimer’s disease biomarkers” Authors: You Cheng, Yingnan He Karthik Gopinath, Benjamin Billot, Juan Eugenio…

“Deep normative modelling reveals insights into early-stage Alzheimer’s disease using multi-modal neuroimaging data” Authors: Ana Lawry Aguila, Luigi Lorenzini, Mohammed Janahi,…

“Accrual of Alzheimer’s disease pathology as a function of proximity to parental dementia onset” Authors: Elina T. Ziukelis, Elijah Mak, Craig Ritchie, John…

“Grey-Matter Structure Markers of Alzheimer’s Disease, Alzheimer’s Conversion, Functioning and Cognition: A Meta-Analysis Across 11 Cohorts” Authors: Baptiste Couvy-Duchesne, Vincent Frouin,…

“Soluble Aβ pathology predicts neurodegeneration and cognitive decline independently on p-tau in the earliest Alzheimer’s continuum: Evidence across two independent cohorts”…

“Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study” Authors: Julie E Oomens, Veerle van Gils, Stephanie J B…

“Blood-brain barrier permeable β-blockers association with Alzheimer’s disease cerebrospinal fluid biomarkers levels in non-demented individuals” Authors:  Mariateresa Buongiorno, Gonzalo Sánchez-Benavides, Clara…

“Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia” Authors: Luigi Lorenzini, Alessio…

“Alzheimer’s disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals” Authors: Luigi Lorenzini, Lyduine E. Collij, Niccoló Tesi, Natàlia Vilor-Tejedor, Silvia…

“Semantic Harmonization of Alzheimer’s Disease Datasets Using AD-Mapper” Authors: Philipp Wegner, Helena Balabin,Mehmet Can Ay, Sarah Bauermeister, Lewis Killin, John Gallacher,…

“Alzheimer’s Disease and Small Vessel Disease Differentially Affect White Matter Microstructure” Authors: Mario Tranfa, Luigi Lorenzini, Lyduine E. Collij, David Vállez García, Silvia Ingala, Giuseppe Pontillo, Leonard…

“Validation of the brain health index in the European Prevention of Alzheimer’s Dementia cohort” Authors: Jodi K. Watt, David Alexander Dickie,…

“Facilitating clinical use of the Amsterdam Instrumental Activities of Daily Living Questionnaire: Normative data and a diagnostic cutoff value” Authors: Merel…

“Modifiable dementia risk factors and AT(N) biomarkers: findings from the EPAD cohort” Authors: Eddy Roccati, Aidan David Bindoff, Jessica Marie Collins,…

“Memory performance mediates subjective sleep quality associations with cerebrospinal fluid Alzheimer’s disease biomarker levels and hippocampal volume among individuals with mild…

“Identification of preclinical dementia according to ATN classification for stratified trial recruitment A machine learning approach“ Authors: Ivan Koychev, Evgeniy Marinov,…

“Data-Driven Thresholding Statistically Biases ATN Profiling across Cohort Datasets” Authors: Y. Salimi, D. Domingo-Fernández, M. Hofmann-Apitius, C. Birkenbihl, the Alzheimer’s Disease…